Young stem cells make rapidly aging mice live longer and healthier
User comments:
[2012-03-04 08:17:28] tagosan - How were the stem ...
How were the stem cells extracted from the young mice?
[2012-02-06 04:55:55] batmanpronz - Where in the young ...Where in the young mice were the stem cells isolated from?
[2012-01-20 20:02:58] upmc - Continued from ...Continued from below: Instead, they appear to be secreting factors that promote regeneration. Young stem cells improved the performance of cells from both progeroid and very old mice. This suggests that stem cells may be beneficial in normal old age.
[2012-01-20 20:02:24] upmc - Yes, this study and ...Yes, this study and several previous ones show that stem cells become dysfunctional with age in animals and humans, just like in progeria. This study indicates that this dysfunction drives the aging process because a dose of young stem cells delays the onset of diseases of old age and extends lifespan in mice with progeria. The young stem cells cannot correct genetic mutations or the defect that drives progeria.
[2012-01-18 15:30:25] billh96007 - Fascinating ...Fascinating research! The question this raises in my mind is, are the stem cells only rectifying whatever genetic damage is bred into these mice to cause progeria, or will they actually confer similar longevity in normally aged mice? Also, apparently the dysfunction stem cells were discovered in the mice with progeria. Are stem cells similarly dysfunctional in normally aged mice?